Joint Mobility™

Joint Mobility™
capsule

*Listed in PDR 2016

Description
Joint Mobility is a nutritional supplement for overall joint health.
Joint Mobility contains Undenatured Type II Collagen, Turmeric Extract (95% Curcumin), Boswellia Extract and Vitamin D3 as active ingredients, and also includes microcrystalline cellulose and silicon dioxide. This supplement is for individuals with joint pain and discomfort caused from normal wear and tear.
Joint Mobility is a powder filled capsule that takes on the yellow color of Turmeric. Compared to more traditional joint supplements, Joint Mobility is a small dose at just 881 mg per day. These smaller capsules are ideal for individuals who have trouble taking large capsules or pills.

Benefits and Research
Many people suffer daily from joint pain and discomfort caused from years of overuse or from being overweight or obese. Joint pain and a loss of mobility can dramatically affect quality of life, making simple everyday activity difficult and painful. The ingredients contained in Joint Mobility work in several different ways to help maintain overall joint health. Curcumin and Boswellia extract have been shown to downregulate the genes involved in chronic inflammation. Vitamin D3 has been shown to help increase collagen production which is needed to maintain overall joint health. Joint Mobility works in several different ways for a multifaceted approach to joint health. The ingredients contained have been shown to inhibit proinflammatory pathways, and also help to prevent the breakdown of joint collagen allowing the body to repair and heal itself.¹

Usage
Take two capsules daily.

Safety and Warnings
Joint Mobility is generally well tolerated. As with any dietary supplement, some gastrointestinal discomfort may be experienced.

How Supplied
Available in capsules.

References
Crowley DC, Lau FC, Sharma P, et al.: Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial. Int J Med Sci 2009, 6:312-321.
Chandran B, Goel A.: A randomized, pilot study to assess the efficacy and safety of curcumin in patients with active rheumatoid arthritis. Phytother Res. 2012 Nov; 26(11): 1719-25. Doi: 10.1002/ptr.4639.Epub 2012 Mar 9.
Dobak J1, Grzybowski J, et al.: 1,25-Dihydroxyvitamin D3 increases collagen production in dermal fibroblasts. J Dermatol Sci. 1994 Aug;8(1):18-24.
Kimmatkar N, Thawani V, et al.: Efficacy and tolerability of Boswellia serrate extract in treatment of osteoarthritis of knee—a randomized double bling placebo controlled trial. Phytomedicine 2003 Jan; 10(1):3-7.
Reuter S, Gupta S, et al.: Epigenetic changes induced by curcumin and other natural compounds. Genes Nutr (2011) 6:93–108.
Takada Y, Ichikawa H, et al.: Acetyl-11-Keto-β-Boswellic Acid Potentiates Apoptosis, Inhibits Invasion, and Abolishes Osteoclastogenesis by Suppressing NF-κΒ and NF- κΒ-Regulated Gene Expression. J Immunol 2006; 176:3127-3140.
¹THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE OR PREVENT ANY DISEASE.

CM PLEX® AND CM PLEX® CREAM

CM PLEX^® AND CM PLEX^® CREAM 
Supports Joint Health and Mobility*

*Listed in PDR 2016

DESCRIPTION
CM Plex^® and CM Plex^® Cream are a softgel and topical cream, respectively, that contain a proprietary blend of cetylated fatty acids, soy, and fish oil.
CM Plex^® is an opaque oil that is insoluble in water. One softgel capsule of CM Plex^® contains 350 mg of cetylated fatty acids, 160 mg of soy oil, and 25 mg of salmon oil. In addition to these active ingredients, each softgel capsule contains glycerin and St. John's Bread.
CM Plex^® Cream is an off-white cream that is insoluble in water. One gram of CM Plex^® Cream contains 7.7 mg of cetylated fatty acids and olive oil. In addition to these active ingredients, CM Plex^® Cream also contains glyceryl stearate, glycerin, lecithin, tocopheryl acetate, benzyl alcohol, phenoxyethanol, carbomer, PEG-100 stearate, sodium hydroxide, methylparaben, propylparaben, butylparaben, ethylparaben, isobutylparaben,and citrus aurantium bergamia (Bergamot) fruit oil.

BENEFITS AND RESEARCH
Cetyl myristoleate and related fatty acids have been proven to improve joint health through their anti-inflammatory effects. A clinical study indicated that subjects exhibited improvements in knee flexion compared to placebo. A second study indicated the cream is effective for improving knee range of motion, ability to climb stairs, rise from a chair and walk, balance, strength, and endurance.*

SUGGESTED USE
Softgels:  Take one to two softgels three times daily with meals.
Cream:  Apply generously onto clean skin and gently massage until the cream disappears. Repeat 3 to 4 times daily as necessary. For maximum results, use both products concurrently.

SAFETY AND WARNINGS
CM Plex^® Softgels and Cream are well tolerated. As with any dietary supplement, some gastrointestinal discomfort may be experienced with CM Plex^® Softgels.

HOW SUPPLIED
CM Plex^® is available in softgels and as a topical cream.

REFERENCES
Hesslink, R et al (2002), Journal of Rheumatology 29, 1708–1712.
Kraemer, WJ et al (2004), Journal of Rheumatology 31, 767–774.
*THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT CURE, OR PREVENT ANY DISEASE.